The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Apr. 16, 2021
Applicant:

SN Bioscience Inc., Seongnam-si, KR;

Inventors:

Young Hwan Park, Wonju-si, KR;

Il Hyun Lee, Incheon, KR;

Assignee:

SN BIOSCIENCE INC., Seongnam-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61P 35/00 (2006.01); A61K 9/50 (2006.01); A61K 9/107 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 9/1075 (2013.01); A61K 9/19 (2013.01); A61K 9/5031 (2013.01); A61K 9/5089 (2013.01); A61P 35/00 (2018.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01);
Abstract

A drug delivery system having an inner core-shell like structure containing a poorly soluble camptothecin compound and a water-soluble camptothecin compound, and an outer amphiphilic polymer shell surrounding the inner core-shell like structure, a manufacturing method therefor, and uses of the drug delivery system in treating cancer are disclosed. The core-shell structured particles form very stable particles and show a mono-distribution of particles before and after freeze-drying. The particles show excellent results compared with existing particles which do not contain the inner core-shell like structure, in animal efficacy tests and pharmacokinetic tests.


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