The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Jul. 05, 2018
Applicant:

Barcode Diagnostics Ltd., Nazareth, IL;

Inventors:

Ronen Eavri, Binyamina, IL;

Annie Sabbah, Haifa, IL;

Felix Badinter, Karmiel, IL;

Raphael Tshuva, Nesher, IL;

Avi Schroeder, Binyamina, IL;

Assignee:

BARCODE DIAGNOSTICS LTD., Nazareth, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 49/00 (2013.01); A61K 49/0017 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method for using bodily fluids in determining the cell-specific potency of drugs is provided. A composition comprising a plurality of types of carriers, wherein each carrier comprises a single-cell lethal amount of a therapeutic agent and a unique barcode identifying that agent and wherein the composition comprises equal numbers of each carrier type, equal concentrations of the agent and equal concentrations of each barcode is also provided. Further, methods useful for studying the therapeutic profile of one or more drugs within a cell microenvironment, including but not limited to a tumor, are provided.


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