The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Sep. 23, 2020
Applicant:

Gen-probe Incorporated, San Diego, CA (US);

Inventors:

David Buse, San Diego, CA (US);

David Howard Combs, San Diego, CA (US);

Norbert D. Hagen, Carlsbad, CA (US);

David Opalsky, San Diego, CA (US);

Bruce Richardson, Los Gatos, CA (US);

Anita Prasad, Los Gatos, CA (US);

Keith Moravick, Los Gatos, CA (US);

Tyler Moore, Los Gatos, CA (US);

Assignee:

GEN-PROBE INCORPORATED, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01); B01L 7/00 (2006.01); G01N 21/64 (2006.01); B01L 9/06 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01L 7/52 (2013.01); G01N 21/6452 (2013.01); B01L 9/06 (2013.01); B01L 2200/141 (2013.01); B01L 2200/142 (2013.01); B01L 2300/042 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/1822 (2013.01); G01N 2021/6482 (2013.01); G01N 2021/6484 (2013.01);
Abstract

An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with front and back surfaces. The front surface includes a row of receptacle wells, and an outer surface of each well has a frustoconical shape, an inner surface of each well receives a receptacle, and each well has a through-hole extending between the inner and outer surfaces thereof. One or more thermal elements in contact with the back surface of the holder alter a temperature(s) of the holder. The apparatus includes multiple optical fibers, and each optical fiber provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A first end of each optical fiber is disposed outside, within, or extends through the through-hole of a corresponding well, and a second end of each optical fiber is in optical communication with the excitation signal source and/or the emission signal detector.


Find Patent Forward Citations

Loading…