The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Apr. 08, 2019
Advanced Cell Diagnostics, Inc., Newark, CA (US);
Yuling Luo, Newark, CA (US);
Xiao-Jun Ma, Newark, CA (US);
Steve Chen, Newark, CA (US);
Nan Su, Newark, CA (US);
Emerald Doolittle, Newark, CA (US);
Bingqing Zhang, Newark, CA (US);
Xiaoming Wang, Newark, CA (US);
Xingyong Wu, Newark, CA (US);
Xiao Yan Pimentel, Newark, CA (US);
Helen Jarnagin, Newark, CA (US);
ADVANCED CELL DIAGNOSTICS, INC., Newark, CA (US);
Abstract
The present invention relates to detection of nucleic acids and provides a composition comprising a Signal Generating Complex, wherein the composition comprises: (A) a pair of target probes (TPs), wherein a first TP of the pair of TPs comprises a nucleic acid sequence comprising two segments; (B) a pair of base PPAs comprising the first and second base PPAs, wherein the first base PPA comprises a nucleic acid sequence comprising three segments; (C) a set of extension PPAs comprising the first and second extension PPAs, wherein the first extension PPA comprises a nucleic acid sequence comprising two segments; (D) a plurality of pre-amplifiers (PAs), wherein the PAs comprise a nucleic acid sequence comprising three segments; (E) a plurality of amplifiers (AMPs), wherein the AMPs comprise a nucleic acid sequence comprising two segments; and (F) a plurality of label probes (LPs), wherein the LPs comprise a nucleic acid sequence comprising two segments.