The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Jan. 31, 2020
Applicant:
University of Washington, Seattle, WA (US);
Inventors:
George Stamatoyannopoulos, Seattle, WA (US);
John Stamatoyannopoulos, Seattle, WA (US);
Assignee:
UNIVERSITY OF WASHINGTON, Seattle, WA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/10 (2006.01); C12N 15/85 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 48/005 (2013.01); C12N 15/113 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/141 (2013.01); C12N 2740/15043 (2013.01); C12N 2740/16043 (2013.01); C12N 2830/40 (2013.01);
Abstract
Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors.