The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Feb. 07, 2022
Applicant:
Lanzatech, Inc., Skokie, IL (US);
Inventors:
Fungmin Liew, Chicago, IL (US);
Michael Koepke, Chicago, IL (US);
Assignee:
LanzaTech, Inc., Skokie, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 15/74 (2006.01); C12P 7/42 (2006.01); C12P 7/18 (2006.01); C12N 9/00 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/1096 (2013.01); C12N 9/93 (2013.01); C12N 15/74 (2013.01); C12P 7/18 (2013.01); C12P 7/42 (2013.01); C12Y 101/01001 (2013.01); C12Y 102/01075 (2013.01); C12Y 102/07005 (2013.01); C12Y 206/01018 (2013.01); C12Y 604/01002 (2013.01);
Abstract
Microorganisms are genetically engineered to produce 3-hydroxypropionate (3-HP). The microorganisms are carboxydotrophic acetogens. The microorganisms produce acetyl-coA using the Wood-Ljungdahl pathway for fixing CO/CO. A β-alanine pyruvate aminotransferase from a microorganism that contains such an enzyme is introduced. Additionally, an acetyl-coA carboxylase may also be introduced. The production of 3-HP can be improved. This can be effected by improved promoters or higher copy number or enzymes that are catalytically more efficient.