The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Feb. 22, 2022
Applicant:

Abclonal Science, Inc., Woburn, MA (US);

Inventors:

Zhenyu Zhu, Lynnfield, MA (US);

Aine Quimby, Newburyport, MA (US);

Dapeng Sun, Lexington, MA (US);

Alicia DiCicco, Salem, MA (US);

Assignee:

ABclonal Science, Inc., Woburn, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C12P 19/34 (2013.01); C12Y 605/01001 (2013.01);
Abstract

A number of T4 DNA ligase mutants exhibiting enhanced ligation activity at temperatures above 37° C. compared to the wild-type ligase were engineered, characterized, and selected via gel electrophoresis of ligation products from a standard ligation assay. T4 Ligase catalyzes the formation of phosphodiester bonds between the 5' and 3′ ends of complementary cohesive ends or blunt ends of duplex DNA, a process that is vital to numerous molecular biology processes including cloning and sequencing.


Find Patent Forward Citations

Zhu, Zhenyu. (2023). T4 dna ligase variants with increased thermostability (U.S. Patent No. 11788082). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11788082

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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