The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Apr. 29, 2020
Applicant:
Innovative Cellular Therapeutics Holdings, Ltd., Grand Cayman, KY;
Inventors:
Chengfei Pu, Shanghai, CN;
Lei Xiao, Rockville, MD (US);
He Sun, Shanghai, CN;
Xiaogang Shen, Shanghai, CN;
Cheng Lu, Shanghai, CN;
Assignee:
Innovative Cellular Therapeutics Holdings, Ltd., George Town, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C07K 14/725 (2006.01); C07K 14/47 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
C12N 9/12 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/4748 (2013.01); C07K 14/7051 (2013.01); C07K 16/2803 (2013.01); C12Y 207/10001 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract
Embodiments relate to compositions and methods for treating solid tumors. For example, the compositions comprise modified cells comprising an isolated polynucleotide comprising a polynucleotide encoding a nuclear factor of activated T cells (NFAT) promoter operatively associated with a polynucleotide encoding FLT3L.