The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Jan. 05, 2019
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Andrew F. Stewart, New York, NY (US);
Courtney Ackeifi, New York, NY (US);
Peng Wang, New York, NY (US);
Bob Devita, New York, NY (US);
Assignee:
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); A61P 5/48 (2006.01); A61P 3/10 (2006.01); A61K 31/437 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0676 (2013.01); A61K 31/437 (2013.01); A61K 38/22 (2013.01); A61P 3/10 (2018.01); A61P 5/48 (2018.01); C12N 2501/335 (2013.01); C12N 2501/727 (2013.01);
Abstract
Disclosed herein are methods of increasing cell proliferation in a population of pancreatic beta cells. Also disclosed are methods of treating a subject for a condition associated with insufficient insulin secretion. Also disclosed is a composition comprising a DYRK1 A inhibitor and a GLP1R agonist. The disclosure further describes a method of regenerating pancreatic beta cells in a transplant patient.