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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11787862 B1

PDFFull Text
Date of Patent:
Oct. 17, 2023

Filed:

Sep. 20, 2017

Bispecific trivalent antibodies binding to claudin6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases

Applicants:

Biontech Ag, Mainz, DE;

Astellas Pharma Inc., Tokyo, JP;

Inventors:

Ugur Sahin, Mainz, DE;

Christiane Stadler, Bensheim, DE;

Leyla Fischer, Gau-Odernheim, DE;

Arne Jendretzki, Mainz-Kostheim, DE;

Özlem Türeci, Mainz, DE;

Fabrice Le Gall, Mainz, DE;

Maria Kreuzberg, Aachen, DE;

Assignees:

BioNTech SE, Mainz, DE;

ASTELLAS PHARMA INC., Tokyo, JP;

Attorney:

Neal, Gerber & Eisenberg LLP

Primary Examiner:

Meera Natarajan

Assistant Examiner:

Cheom-Gil Cheong

Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 15/86 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61P 35/00 (2018.01); C07K 16/28 (2013.01); C12N 15/86 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present invention provides binding agents comprising at least three binding domains, wherein a first binding domain binds to a T cell-specific antigen and a second binding domain and a third binding domain bind to a claudin, and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.

Find Patent Forward Citations

Sahin, Ugur. (2023). Bispecific trivalent antibodies binding to claudin6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases (U.S. Patent No. 11787862). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11787862

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