The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Jun. 07, 2017
Applicant:
Precigen, Inc., Germantown, MD (US);
Inventors:
Rutul Shah, Boyds, MD (US);
Tim Chan, Frederick, MD (US);
Peter Emtage, Lafayette, CA (US);
Ramya Yarlagadda, Gaithersburg, MD (US);
Assignee:
PRECIGEN, INC., Germantown, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01); C07K 14/725 (2006.01); C07K 14/71 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/70503 (2013.01); A61K 39/001104 (2018.08); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70575 (2013.01); C07K 14/70578 (2013.01); C07K 14/70596 (2013.01); C07K 14/71 (2013.01); C07K 16/2803 (2013.01); C12N 5/0636 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/57 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C12N 2510/00 (2013.01);
Abstract
Provided herein are chimeric antigen receptors (CARs) for cancer therapy, and more particularly, CARs containing a scFv from a CD33 monoclonal antibody. Provided are immune effector cells containing such CARs, and methods of treating proliferative disorders such as acute myeloid leukemia (AML), and relapsed or refractory AML.