The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Mar. 31, 2023
Applicant:

Metro International Biotech, Llc, Cambridge, MA (US);

Inventors:

Jonathan N. Kremsky, Worcester, MA (US);

Bruce Szczepankiewicz, Worcester, MA (US);

Karsten Koppetsch, Worcester, MA (US);

Joseph Harris, Cambridge, GB;

Mateusz Pitak, Cambridge, GB;

Martin Bates, Cambridge, GB;

Assignee:

Metro International Biotech, LLC, Worcester, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/048 (2006.01); A61K 31/706 (2006.01); C30B 7/02 (2006.01); C07H 1/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/048 (2013.01); A61K 31/706 (2013.01); C07H 1/06 (2013.01); C30B 7/02 (2013.01);
Abstract

The present disclosure relates to crystalline solids comprising a compound of Formula (I), wherein R is n-propyl, and methods of making compounds of Formula (I) wherein R is C1-C4 alkyl or C2-C4 alkenyl. The present disclosure also relates to crystalline solids comprising a compound of Formula (II), The present disclosure further relates to methods of preparing the crystalline solids, and pharmaceutical preparations of the crystalline solids, and use of such pharmaceutical preparations in treatment of diseases and conditions.


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