The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Dec. 10, 2021
Applicant:

Ildong Pharmaceutical Co., Ltd., Seoul, KR;

Inventors:

Yoonsuk Lee, Hwaseong-si, KR;

Kyung Sun Kim, Hwaseong-si, KR;

Jeong-Ah Kim, Hwaseong-si, KR;

Anna Moon, Hwaseong-si, KR;

Dongkeun Song, Hwaseong-si, KR;

Juyoung Jung, Hwaseong-si, KR;

Jun-Su Ban, Hwaseong-si, KR;

Soo-Jin Lee, Hwaseong-si, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/53 (2006.01); C07D 239/70 (2006.01); C07D 253/08 (2006.01); C07D 487/04 (2006.01); G01N 33/50 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01); G01N 33/5041 (2013.01);
Abstract

The present disclosure provides androgen receptor (AR) and phosphodiesterase 5 (PDE-5) inhibitor compounds of the formula (I): and compositions including said compounds. The compounds can provide dual functionality for inhibiting AR and inhibiting PDE-5. The present disclosure also provides methods of using said compounds and compositions for inhibiting AR and PDE-5 in a biological system or biological sample. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.


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