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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11787766 B1

PDFFull Text
Date of Patent:
Oct. 17, 2023

Filed:

Aug. 17, 2018

Compound having pd-l1 inhibitory activity, preparation method therefor and use thereof

Applicant:

Shanghai Ennovabio Pharmaceuticals Co., Ltd., Shanghai, CN;

Inventors:

Lei Jiang, Shanghai, CN;

Jianwen Deng, Shanghai, CN;

Xiaoli Lu, Shanghai, CN;

Ke Shang, Shanghai, CN;

Jianyong Shou, Shanghai, CN;

Bing Wang, Shanghai, CN;

Danyi Wu, Shanghai, CN;

Xueli Xu, Shanghai, CN;

Yuan Xu, Shanghai, CN;

Yi Zhang, Shanghai, CN;

Mingwei Zheng, Shanghai, CN;

Assignee:

SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD., Shanghai, CN;

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
C07D 213/69 (2006.01); C07D 213/73 (2006.01); C07D 213/84 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 519/00 (2006.01); A61K 31/137 (2006.01); A61K 31/165 (2006.01); A61K 31/4155 (2006.01); A61K 31/437 (2006.01); A61K 31/44 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 39/12 (2006.01); A61K 39/245 (2006.01); A61K 39/29 (2006.01); A61K 45/06 (2006.01); C07C 211/03 (2006.01); C07C 223/02 (2006.01); C07D 231/40 (2006.01);
U.S. Cl.
CPC ...
C07D 213/69 (2013.01); A61K 31/137 (2013.01); A61K 31/165 (2013.01); A61K 31/4155 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 39/12 (2013.01); A61K 39/245 (2013.01); A61K 39/29 (2013.01); A61K 45/06 (2013.01); C07C 211/03 (2013.01); C07C 223/02 (2013.01); C07D 213/73 (2013.01); C07D 213/84 (2013.01); C07D 231/40 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided are a compound for the prevention and treatment of diseases associated with PD-L1, a preparation method therefor and use thereof. Specifically, provided are the compound of formula I, the stereoisomer and the racemate thereof, or pharmaceutically acceptable salts thereof, and also provided is an application thereof in the preparation of a drug for the prevention and treatment of diseases associated with PD-L1.

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