The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Feb. 14, 2019
Applicants:

Children's National Medical Center, Washington, DC (US);

The United States of America, As Represented BY the Secretary, Department of Health & Human Services, Bethesda, MD (US);

Inventors:

Martin John Schnermann, Rockville, MD (US);

Peter C. W. Kim, Washington, DC (US);

Jaepyeong Cha, Laurel, MD (US);

Roger Rauhauser Nani, Fredrick, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); C07D 209/10 (2006.01); A61K 49/00 (2006.01); G01N 21/64 (2006.01); G01N 33/533 (2006.01); G01N 33/58 (2006.01); C07D 403/12 (2006.01); C09K 11/06 (2006.01);
U.S. Cl.
CPC ...
C07D 209/10 (2013.01); A61K 49/006 (2013.01); A61K 49/0032 (2013.01); A61K 49/0058 (2013.01); C07D 403/12 (2013.01); C09K 11/06 (2013.01); G01N 21/6428 (2013.01); G01N 33/533 (2013.01); G01N 33/582 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems are disclosed. Certain heptamethine cyanines exhibit renal system specificity, while others exhibit biliary system specificity. The compounds may be used for diagnostic purposes and/or for visualization of renal or biliary systems during surgery.


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