The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Jan. 08, 2021
Applicants:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Rongliang Chen, San Diego, CA (US);

Padma Manam, San Diego, CA (US);

LU Zeng, San Diego, CA (US);

Inventors:

Rongliang Chen, San Diego, CA (US);

Padma Manam, San Diego, CA (US);

Lu Zeng, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); C07D 401/14 (2006.01); A61K 31/4725 (2006.01); A61K 31/519 (2006.01); C08B 37/16 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6951 (2017.08); A61K 31/4725 (2013.01); A61K 31/519 (2013.01); C07D 401/14 (2013.01); C08B 37/0015 (2013.01);
Abstract

Disclosed is a complex of a compound of Formula 1, a stereoisomer thereof, or a tautomer of the compound of Formula 1 or stereoisomer thereof, and a cyclodextrin, in which the complex is an amorphous solid. This disclosure also relates to materials and methods for preparing the complex, to pharmaceutical compositions which contain the complex, and to the use of the complex to treat Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.


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