The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Sep. 13, 2017
Applicant:
Angiocrine Bioscience, Inc., San Diego, CA (US);
Inventors:
Michael Daniel Ginsberg, San Diego, CA (US);
Daniel Joseph Nolan, Hawthorne, NY (US);
Liang Qiang, Philadelphia, PA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); C12N 5/071 (2010.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01); A61K 35/44 (2015.01); A61K 35/13 (2015.01); A61K 35/30 (2015.01); A61L 27/38 (2006.01); C12N 5/09 (2010.01);
U.S. Cl.
CPC ...
A61K 35/44 (2013.01); A61K 35/13 (2013.01); A61K 35/30 (2013.01); A61L 27/3808 (2013.01); A61L 27/3878 (2013.01); A61L 27/3886 (2013.01); C07K 14/005 (2013.01); C12N 5/069 (2013.01); C12N 5/0622 (2013.01); C12N 5/0693 (2013.01); C12N 5/0697 (2013.01); C12N 15/86 (2013.01); C12N 2502/086 (2013.01); C12N 2502/28 (2013.01); C12N 2710/10322 (2013.01);
Abstract
The present invention relates, in part, to blood-brain barrier-like tissues that comprise engineered E40RF1+ endothelial cells, and to various compositions and methods useful for making and using such blood-brain barrier-like tissues—both in vitro and in vivo.