The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Dec. 08, 2020
Applicant:

Somerset Therapeutics Llc, Hollywood, FL (US);

Inventors:

Mandar V. Shah, Rockaway, NJ (US);

Veerappan Subramanian, Warren, NJ (US);

Ilango Subramanian, Warren, NJ (US);

Aman Trehan, Hillsborough, NJ (US);

Assignee:

Somerset Therapeutics, LLC, Hollywood, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5575 (2006.01); A61K 31/14 (2006.01); A61K 9/08 (2006.01); A61K 47/44 (2017.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01); A61K 31/165 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 31/5575 (2013.01); A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 31/14 (2013.01); A61K 31/165 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/186 (2013.01); A61K 47/26 (2013.01); A61K 47/44 (2013.01);
Abstract

The present invention relates to ophthalmic compositions comprising from 0.005% to 0.02% bimatoprost by weight, less than 100 ppm benzalkonium chloride, and a secondary penetration enhancer that detectably enhances penetration of bimatoprost into a mammalian eye such that elevated intraocular pressure is effectively reduced to an extent statistically comparable to compositions comprising higher amounts of bimatoprost and benzalkonium chloride. Further, the invention also provides a process of preparing such compositions and methods of their use for lowering intraocular pressure and treating glaucoma.


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