The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Mar. 09, 2022
Applicant:

National Yang Ming Chiao Tung University, Hsinchu, TW;

Inventors:

Jinn-Moon Yang, Hsinchu, TW;

Po-Shiuan Hsieh, Taipei, TW;

Chih-Heng Huang, Hsinchu, TW;

Yu-Hsiu Chang, Taipei, TW;

Nikhil Pathak, Hsinchu, TW;

Yen-Chao Hsu, Hsinchu, TW;

Yun-Ti Chen, Tainan, TW;

Nung-Yu Hsu, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 31/14 (2006.01); A61K 31/675 (2006.01); A61K 31/402 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/402 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61P 31/14 (2018.01);
Abstract

Disclosed herein is a method against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The method includes administering to a subject in need thereof a first active ingredient selected from the group consisting of methotrexate (MIX) and a pharmaceutically acceptable salt thereof, and a second active ingredient selected from the group consisting of remdesivir and a pharmaceutically acceptable salt thereof. A molar ratio of the first active ingredient to the second active ingredient ranges from 1:13 to 1:25.


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