The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2023

Filed:

Jul. 02, 2015
Applicant:

Novartis Ag, Basel, CH;

Inventors:

David Hook, Rheinfelden, CH;

Bin Hu, Green Brook, NJ (US);

Florian Karl Kleinbeck, Zurich, CH;

Ulrich Meier, Riehen, CH;

Sibylle Mueller, Frenkendorf, CH;

Jean-Paul Mutz, Blotzheim, FR;

Jan Schlomach, Basel, CH;

Paul Allen Sutton, Getzville, NY (US);

Liladhar Murlidhar Waykole, Succasunna, NJ (US);

Bernhard Wietfeld, Efringen-Kirchen, DE;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/22 (2006.01); A61P 9/10 (2006.01); A61P 9/06 (2006.01); A61P 25/02 (2006.01); C07C 229/34 (2006.01); A61P 9/12 (2006.01); A61P 25/06 (2006.01); A61K 31/4178 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
A61K 31/22 (2013.01); A61P 9/06 (2018.01); A61P 9/10 (2018.01); A61P 9/12 (2018.01); A61P 25/02 (2018.01); A61P 25/06 (2018.01); C07C 229/34 (2013.01); A61K 31/4178 (2013.01); A61K 31/423 (2013.01); A61K 2300/00 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.


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