The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Nov. 05, 2015
Applicants:

Fujikura Kasei Co., Ltd., Tokyo, JP;

National University Corporation Chiba University, Chiba, JP;

Inventors:

Rika Nakamura, Kuki, JP;

Hideyuki Kuroda, Kuki, JP;

Go Tomiyoshi, Kuki, JP;

Takaki Hiwasa, Chiba, JP;

Masaki Takiguchi, Chiba, JP;

Naokatsu Saeki, Chiba, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/573 (2006.01); C12Q 1/25 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C12Q 1/25 (2013.01); C12Q 1/68 (2013.01); G01N 33/53 (2013.01);
Abstract

The present inventors have surprisingly found that a deoxyhypusine synthase (DHPS) gene, which was previously reported to correlate with prostate cancer and cervical cancer, is highly responsive to arteriosclerosis or digestive system cancer, whereby the gene can be used as a desired marker for arteriosclerosis or digestive system cancer. The present invention has been accomplished on the basis of this finding. Specifically, the present invention provides a method for determining arteriosclerosis or digestive system cancer, which method includes detecting expression of a deoxyhypusine synthase gene in a test sample (preferably a blood sample), and determining arteriosclerosis or digestive system cancer of a test subject from which the test sample has been obtained, on the basis of an increase in the gene expression as an index.


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