The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Jul. 01, 2019
Applicant:

Cellular Research, Inc., San Jose, CA (US);

Inventors:

Christina Fan, San Jose, CA (US);

Olaf Zoellner, San Jose, CA (US);

Assignee:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); G16B 99/00 (2019.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); C12Q 1/6804 (2018.01); G16Z 99/00 (2019.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6823 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/68 (2018.01); G16B 25/10 (2019.01); G16H 20/13 (2018.01); G16H 10/20 (2018.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C12N 15/1006 (2013.01); C12N 15/1096 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6823 (2013.01); C12Q 1/6869 (2013.01); G01N 33/505 (2013.01); G01N 33/54306 (2013.01); G01N 33/54313 (2013.01); G01N 33/6842 (2013.01); G01N 33/6857 (2013.01); G16B 99/00 (2019.02); G16Z 99/00 (2019.02); B01J 2219/00646 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01); C07K 2319/01 (2013.01); G16B 25/10 (2019.02); G16H 10/20 (2018.01); G16H 20/13 (2018.01);
Abstract

Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.


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