The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Jan. 25, 2019
Applicant:

Alverix, Inc., Franklin Lakes, NJ (US);

Inventors:

Patrick T. Petruno, San Jose, CA (US);

John Francis Petrilla, Palo Alto, CA (US);

Michael J. Brosnan, Fremont, CA (US);

Rong Zhou, Sunnyvale, CA (US);

Daniel B. Roitman, Menlo Park, CA (US);

Bo U. Curry, Redwood City, CA (US);

Assignee:

ALVERIX, INC., Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/558 (2006.01); G01N 21/62 (2006.01); G01N 21/63 (2006.01); G01N 21/64 (2006.01); G01N 21/84 (2006.01); G01N 21/17 (2006.01); G01N 21/27 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54388 (2021.08); G01N 21/17 (2013.01); G01N 21/274 (2013.01); G01N 21/6428 (2013.01); G01N 21/8483 (2013.01); G01N 33/54393 (2013.01); G01N 33/558 (2013.01); G01N 33/58 (2013.01); G01N 2021/6439 (2013.01); G01N 2201/062 (2013.01); G01N 2201/067 (2013.01); Y10S 435/805 (2013.01); Y10S 435/823 (2013.01); Y10S 436/807 (2013.01); Y10S 436/809 (2013.01); Y10S 436/81 (2013.01); Y10S 436/823 (2013.01); Y10T 436/25125 (2015.01);
Abstract

A diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port constructed and arranged to receive a test strip that includes a flow path for a fluid sample, a sample receiving zone couple to the flow path, a label that specifically binds a target analyte, a detection zone coupled to the flow path and comprising a test region exposed for optical inspection and having an immobilized test reagent that specifically binds the target analyte, and at least one reference feature. The reader is operable to obtain light intensity measurements from exposed regions of the test strip when the test strip is loaded in the port. The data analyzer is operable to perform operations including at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.


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