The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Dec. 22, 2022
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Xiuyu Cai, San Diego, CA (US);

Joseph Francis Pinto, Solana Beach, CA (US);

Thomas A. Baker, San Diego, CA (US);

Tracy Helen Fung, San Mateo, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); B01L 3/00 (2006.01); G01J 1/44 (2006.01); G01N 33/58 (2006.01); G02B 6/42 (2006.01); H01L 27/144 (2006.01); H01L 27/146 (2006.01); H01L 31/02 (2006.01); H01L 31/0216 (2014.01); H01L 31/0232 (2014.01); G01N 21/05 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); B01L 3/5085 (2013.01); B01L 3/50853 (2013.01); B01L 3/502715 (2013.01); G01J 1/44 (2013.01); G01N 21/6454 (2013.01); G01N 33/582 (2013.01); G02B 6/4214 (2013.01); H01L 27/1446 (2013.01); H01L 27/14609 (2013.01); H01L 27/14623 (2013.01); H01L 27/14629 (2013.01); H01L 31/02019 (2013.01); H01L 31/02164 (2013.01); H01L 31/02165 (2013.01); H01L 31/02327 (2013.01); G01N 21/05 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Light detection devices and related methods are provided. The devices may comprise a reaction structure for containing a reaction solution with a relatively high or low pH and a plurality of reaction sites that generate light emissions. The devices may comprise a device base comprising a plurality of light sensors, device circuitry coupled to the light sensors, and a plurality of light guides that block excitation light but permit the light emissions to pass to a light sensor. The device base may also include a shield layer extending about each light guide between each light guide and the device circuitry, and a protection layer that is chemically inert with respect to the reaction solution extending about each light guide between each light guide and the shield layer. The protection layer prevents reaction solution that passes through the reaction structure and the light guide from interacting with the device circuitry.


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