The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Nov. 16, 2018
The General Hospital Corporation, Boston, MA (US);
Gpb Scientific, Llc, Richmond, CA (US);
Verinata Health, Inc., Redwood City, CA (US);
Daniel Shoemaker, San Diego, CA (US);
Mehmet Toner, Charlestown, MA (US);
Ravi Kapur, Sharon, MA (US);
Roland B. Stoughton, The Sea Ranch, CA (US);
Ronald W. Davis, Palo Alto, CA (US);
The General Hospital Corporation, Boston, MA (US);
GPB Scientific, LLC, Richmond, VA (US);
Verinata Health, Inc., Redwood City, CA (US);
Abstract
The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population of maternal cells in a sample and to test fetal abnormalities, e.g. aneuploidy. The present invention involves labeling regions of genomic DNA in each cell in said mixed sample with different labels wherein each label is specific to each cell and quantifying the labeled regions of genomic DNA from each cell in the mixed sample. More particularly the invention involves quantifying labeled DNA polymorphisms from each cell in the mixed sample.