The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Sep. 24, 2019
Applicant:
Hudsonalpha Institute for Biotechnology, Huntsville, AL (US);
Inventors:
Richard M Myers, Huntsville, AL (US);
Brian S Roberts, Huntsville, AL (US);
Assignee:
HudsonAlpha Institute for Biotechnology, Huntsville, AL (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6848 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/686 (2018.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6848 (2013.01); C12N 15/11 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6874 (2013.01); C12N 2310/113 (2013.01); C12N 2320/10 (2013.01); C12N 2330/31 (2013.01); C12Q 2521/501 (2013.01); C12Q 2525/186 (2013.01); C12Q 2525/191 (2013.01); C12Q 2525/207 (2013.01); C12Q 2525/301 (2013.01); C12Q 2537/163 (2013.01);
Abstract
A method of reducing the abundance of a non-target micro-RNA (miRNA) that is part of a group of miRNAs is provided, including: (a) annealing a complementary region of a blocking nucleic acid to a binding site at a first end of the unwanted miRNA, ligating an adenylated nucleic acid adapter to the group of miRNAs, and performing RT-PCR on group of miRNAs. Kits and compounds for use with the method are also provided.