The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Apr. 26, 2021
Applicant:
Northwestern University, Evanston, IL (US);
Inventor:
Rishi Arora, Chicago, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61B 5/00 (2006.01); A61B 5/316 (2021.01); A61B 5/361 (2021.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61B 5/316 (2021.01); A61B 5/361 (2021.01); A61B 5/4848 (2013.01); C12Y 106/03 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01);
Abstract
Disclosed herein are pharmaceutical compositions and methods for inhibiting oxidative stress in a subject having atrial or ventricular arrhythmias, ventricular failure or heart failure. The methods include administering an effective amount of a NOX2 inhibitor agent to the subject, wherein said administering is under conditions such that a level of oxidative stress in myocardial tissue is reduced or eliminated. The pharmaceutical compositions include a NOX2 inhibitor agent.