The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Jun. 08, 2018
Applicant:
Georg-august-universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin, Goettingen, DE;
Inventors:
Wolfram-Hubertus Zimmermann, Goettingen, DE;
Maria Zafeiriou, Goettingen, DE;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0793 (2010.01); C12N 5/079 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0619 (2013.01); C12N 5/0622 (2013.01); G01N 33/5058 (2013.01); C12N 2500/30 (2013.01); C12N 2500/90 (2013.01); C12N 2501/115 (2013.01); C12N 2501/15 (2013.01); C12N 2501/42 (2013.01); C12N 2503/02 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2513/00 (2013.01); C12N 2533/54 (2013.01);
Abstract
The present invention relates to the field of in vitro 3D modeling of neural tissues, particularly of the brain. There is the need of developing cell culture models of neural tissue that reflect physiological aspects of neural tissue. The present invention provides methods of producing bioengineered neuronal organoids (BENOs) which form functional neuronal networks. The present invention also relates to uses and applications of the produced BENOs, e.g., in the fields of drug screening and personalized medicine.