The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
May. 02, 2023
Anti-angptl3 antibodies suitable for high concentration compositions and subcutaneous administration
Applicant:
Novo Nordisk A/s, Bagsvaerd, DK;
Inventors:
Anette Henriksen, Alleroed, DK;
Thomas Nylandsted Krogh, Jyllinge, DK;
Per J. Greisen, Belmont, MA (US);
Thomas Egebjerg, Ganloese, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07K 16/22 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61P 3/10 (2018.01); A61K 2039/505 (2013.01); C07K 2317/35 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention relates to novel monovalent anti-ANGPTL3 antibodies for use in medicine and in particular for lowering of plasma triglycerides levels in patients in need thereof, such as patients suffering from or at risk of hypertriglyceridemia and/or cardiovascular disease, such as atherosclerotic cardiovascular disease (ASCVD) as well as pharmaceutical compositions suitable for subcutaneous administration and kits comprising such compounds and compositions.