The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Feb. 05, 2021
Applicant:

Biotest Ag, Dreieich, DE;

Inventors:

Wolfgang Möller, Oberursel, DE;

Dieter Rudnick, Dreieich, DE;

Oliver Maneg, Bad Homburg, DE;

Michael Rodemer, Rodgau, DE;

Matthias Germer, Langen, DE;

Veit Braun, Mainz, DE;

Assignee:

BIOTEST AG, Dreieich, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61K 39/395 (2006.01); A61K 47/18 (2017.01); C07K 16/06 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01); C07K 16/14 (2006.01); C07K 1/30 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1275 (2013.01); A61K 9/0019 (2013.01); A61K 39/395 (2013.01); A61K 39/39591 (2013.01); A61K 47/183 (2013.01); C07K 16/065 (2013.01); C07K 16/121 (2013.01); C07K 16/125 (2013.01); C07K 16/1232 (2013.01); C07K 16/1267 (2013.01); C07K 16/14 (2013.01); A61K 2039/507 (2013.01); C07K 1/30 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01);
Abstract

An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5% IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5a and/or substantially no C3a. The antibody preparation can have medical uses.


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