The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Sep. 13, 2017
Applicant:
The Jackson Laboratory, Bar Harbor, ME (US);
Inventors:
Albert Cheng, Bar Harbor, ME (US);
Aziz Taghbalout, Bar Harbor, ME (US);
Nathaniel Jillette, Bar Harbor, ME (US);
Assignee:
The Jackson Laboratory, Bar Harbor, ME (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C07K 14/47 (2006.01); C12N 9/06 (2006.01); C12N 9/02 (2006.01); C12N 9/24 (2006.01); C12N 15/09 (2006.01); C07K 14/315 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); C07K 14/315 (2013.01); C12N 9/0032 (2013.01); C12N 9/0069 (2013.01); C12N 9/0071 (2013.01); C12N 9/22 (2013.01); C12N 9/2497 (2013.01); C12N 15/09 (2013.01); C12N 15/113 (2013.01); C12N 15/85 (2013.01); C12N 15/902 (2013.01); C12Y 114/11 (2013.01); C07K 2319/09 (2013.01); C07K 2319/85 (2013.01); C07K 2319/90 (2013.01); C12Y 113/1102 (2013.01); C12Y 301/21001 (2013.01);
Abstract
Provided herein are, inter alia, compositions and methods for demethylating and methylating a target DNA sequences in a mammalian cell. The compositions and methods are, useful for activity modulation of a targeted gene, or to create a gene regulatory network.