The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Oct. 31, 2018
Applicants:

Yamasa Corporation, Choshi, JP;

National University Corporation Tokai National Higher Education and Research System, Nagoya, JP;

Inventors:

Yoshihito Ueno, Gifu, JP;

Yusuke Maeda, Gifu, JP;

Ryohei Kajino, Gifu, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 19/10 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07H 19/10 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01);
Abstract

A nucleoside that is more practical for RNA pharmaceuticals and other applications and use thereof is represented by formula (1) or (2) below, or a salt thereof: (In formula (1), Rrepresents a hydrogen atom, a hydroxyl group, a hydroxyl group in which a hydrogen atom is substituted by an alkyl group or alkenyl group, or a protected group, and in formula (2), X represents a halogen atom. In formula (1) and formula (2), Rand Rmay be the same or different, and each represents a hydrogen atom etc., Rrepresents NHR(in which Rrepresents a hydrogen atom etc., and B represent represents any of a purine-9-yl group, 2-oxo-pyrimidin-1-yl group, substituted purine-9-yl group or substituted 2-oxo-pyrimidin-1-yl group).


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