The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Apr. 28, 2023
Applicant:
King Abdulaziz University, Jeddah, SA;
Inventors:
Irfan Ahmad Rather, Jeddah, SA;
Majid Rasool Kamli, Jeddah, SA;
Khalid Rehman Hakeem, Jeddah, SA;
Ahmad Firoz, Jeddah, SA;
Jamal S. M. Sabir, Jeddah, SA;
Mohmmad Younus Wani, Jeddah, SA;
Yong Ha Park, Gyeongsanbuk-do, KR;
Yan Yan Hor, Gyeongsanbuk-do, KR;
Assignee:
KING ABDULAZIZ UNIVERSITY, Jeddah, SA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/06 (2006.01); A61P 31/10 (2006.01); C07F 15/04 (2006.01); A01P 3/00 (2006.01); A01N 59/16 (2006.01); A01N 59/20 (2006.01); A01N 55/02 (2006.01); C07C 209/60 (2006.01);
U.S. Cl.
CPC ...
C07F 15/06 (2013.01); A01N 55/02 (2013.01); A01N 59/16 (2013.01); A01N 59/20 (2013.01); A01P 3/00 (2021.08); A61P 31/10 (2018.01); C07F 15/045 (2013.01); C07F 15/065 (2013.01); C07C 209/60 (2013.01);
Abstract
Provided herein are homoleptic metal coordination complexes that induce cellular apoptosis and cell cycle arrest in G0/G1 phase in fungus, such asspp. Also disclosed are methods of inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosed compounds exhibit anti-activity against fluconazole resistant and sensitive strains ofat low concentrations.