The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Mar. 29, 2021
Applicants:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Arena Pharmaceuticals, Inc.;

Inventors:

Kai Gerlach, Ingelheim am Rhein, DE;

Graeme Semple, San Diego, CA (US);

Yifeng Xiong, San Diego, CA (US);

Barbara Bertani, Ingelheim am Rhein, DE;

Marco Ferrara, Ingelheim am Rhein, DE;

Giacomo Fossati, Ingelheim am Rhein, DE;

Scott Hobson, Ingelheim am Rhein, DE;

Uta Friederike Lessel, Ingelheim am Rhein, DE;

Frank Runge, Ingelheim am Rhein, DE;

Ursula Mueller-Vieira, Ingelheim am Rhein, DE;

Julian Wippich, Ingelheim am Rhein, DE;

Assignees:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Arena Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01);
Abstract

The invention relates to substituted 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) for use as a medicament, pharmaceutical compositions comprising the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.


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