The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Dec. 09, 2021
Applicant:

New Jersey Institute of Technology, Newark, NJ (US);

Inventor:

Kamalesh Sirkar, Bridgewater, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 213/06 (2006.01); B01D 9/00 (2006.01); C07C 213/10 (2006.01); B01D 61/28 (2006.01); B01D 11/04 (2006.01); C07D 403/06 (2006.01); B01D 9/02 (2006.01);
U.S. Cl.
CPC ...
B01D 9/0059 (2013.01); B01D 9/02 (2013.01); B01D 11/0492 (2013.01); B01D 61/28 (2013.01); C07C 213/06 (2013.01); C07C 213/10 (2013.01); C07D 403/06 (2013.01); B01D 2009/0086 (2013.01);
Abstract

The present invention is directed to a method of producing active pharmaceutical ingredients (APIs). The method includes subjecting a reaction mixture with an API precursor to solvent extraction to produce a reactant stream with the API precursor. The method includes concentrating the API precursor in the reactant stream using at least one membrane. The method includes carrying out a reaction in a membrane reactor. The method includes separating the API precursor from the reaction stream using a separator. The method includes crystallizing the API precursor using a crystallizer to produce APIs.


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