The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2023

Filed:

Feb. 19, 2020
Applicants:

Institut Pasteur, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Pierre Charneau, Paris, FR;

Philippe Despres, Sant-Denis, FR;

Melissanne De Wispelaere, Paris, FR;

Philippe Souque, Plaisir, FR;

Marie-Pascale Frenkiel, Levallois Perret, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); C07K 14/18 (2006.01); A61K 9/19 (2006.01); A61K 47/26 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 9/19 (2013.01); A61K 47/26 (2013.01); C07K 14/005 (2013.01); C07K 14/1825 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/54 (2013.01); A61K 2039/552 (2013.01); A61K 2039/575 (2013.01); C07K 2319/40 (2013.01); C12N 2740/15043 (2013.01); C12N 2740/16043 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24123 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24171 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to a lentiviral vector-based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein, in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector, uses and methods to prevent a JEV infection in a mammalian host, especially in a human or an animal host, in particular a pig or a piglet, preferably a domestic pig or a domestic piglet.


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