The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2023
Filed:
Jan. 14, 2022
Applicant:
Versi Group, Llc, Gladstone, NJ (US);
Inventor:
Ebrahim Versi, Gladstone, NJ (US);
Assignee:
DMK PHARMACEUTICALS CORPORATION, Somerville, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61P 25/30 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/135 (2013.01); A61P 25/30 (2018.01);
Abstract
The present invention relates to a method of treating drug addiction and reducing dependence or tolerance on a dependence-inducing opiate drug, wherein the method comprises administering to a subject a compound having the structure of formula (I): having the IUPAC name of (−)3-((S)-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)(3-thienyl)methyl)phenol, or pharmaceutically acceptable esters or salts thereof, wherein the compound has activity on the mu, delta and kappa opioid receptors thereby providing added analgesia with an improved therapeutic index and reduced risk of respiratory depression.