The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Apr. 06, 2020
Applicant:
University of Utah Research Foundation, Salt Lake city, UT (US);
Inventors:
Andrew S. Dixon, Salt Lake City, UT (US);
Shawn Owen, Salt Lake City, UT (US);
Assignee:
UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/58 (2006.01); G01N 33/542 (2006.01); C12Q 1/66 (2006.01); C07K 16/24 (2006.01); C12Q 1/6804 (2018.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); C07K 16/241 (2013.01); C12Q 1/66 (2013.01); G01N 33/542 (2013.01); G01N 33/581 (2013.01); C07K 2317/24 (2013.01); C12Q 1/6804 (2013.01); G01N 2333/525 (2013.01);
Abstract
Split enzyme reporter systems are disclosed for detecting an analyte in a mixture. Fragments of the split enzyme may be covalently bound to targeting domains that bind to target regions of an analyte, thereby causing formation of an active complex. Some split enzyme reporter systems can be used to detect an analyte without the use of analyte immobilization, blocking, or wash steps. Some reporter systems also enable rapid detection of the analyte of interest.