The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Apr. 06, 2018
Applicant:
Universität Zu Köln, Cologne, DE;
Inventors:
Melanie von Brandenstein, Lindlar, DE;
Ali Tok, Hürth, DE;
Assignee:
Universität zu Köln, Cologne, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C07K 16/18 (2006.01); G01N 33/563 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); C07K 16/18 (2013.01); G01N 33/563 (2013.01); G01N 2800/367 (2013.01);
Abstract
The present invention relates to a method for determining the fertility of spermatozoa, said method comprising determining the total content of Vimentin variant 3 (Vim3) per spermatozoon and/or the spatial localization of the Vim3 in the spermatozoa, wherein a decreased amount of total content and/or decreased amount of (or even missing) accumulation of Vim3 in the mid piece of the spermatozoa indicates decreased fertility. Further, the present invention refers to a dipstick usable for this method. Moreover, the present invention relates to further methods and uses in the context of the present invention.