The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Sep. 28, 2020
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Yu-Hwa Lo, San Diego, CA (US);

Yuanyuan Han, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 15/14 (2006.01); G01N 21/51 (2006.01); G01N 21/53 (2006.01); G01F 17/00 (2006.01); G01N 15/10 (2006.01); G02B 21/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6486 (2013.01); G01N 15/147 (2013.01); G01N 15/1434 (2013.01); G01N 15/1459 (2013.01); G01N 21/51 (2013.01); G01N 21/53 (2013.01); G01F 17/00 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/144 (2013.01); G01N 2015/145 (2013.01); G01N 2015/1447 (2013.01); G01N 2201/06113 (2013.01); G02B 21/002 (2013.01);
Abstract

Methods, systems, and devices are disclosed for imaging particles and/or cells using flow cytometry. In one aspect, a method includes transmitting a light beam at a fluidic channel carrying a fluid sample containing particles; optically encoding scattered or fluorescently-emitted light at a spatial optical filter, the spatial optical filter including a surface having a plurality of apertures arranged in a pattern along a transverse direction opposite to particle flow and a longitudinal direction parallel to particle flow, such that different portions of a particle flowing over the pattern of the apertures pass different apertures at different times and scatter the light beam or emit fluorescent light at locations associated with the apertures; and producing image data associated with the particle flowing through the fluidic channel based on the encoded optical signal, in which the produced image data includes information of a physical characteristic of the particle.


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