The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Dec. 17, 2018
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Stephen Turner, Eugene, OR (US);

Jonas Korlach, Camas, WA (US);

Steven Warren, New York, NY (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B82Y 10/00 (2011.01); B82Y 15/00 (2011.01); C12Q 1/68 (2018.01); G01N 27/41 (2006.01); G11C 19/00 (2006.01); H01L 29/06 (2006.01); H01L 29/16 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01); G01N 27/414 (2006.01); G11C 19/28 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); B82Y 10/00 (2013.01); B82Y 15/00 (2013.01); C12Q 1/6874 (2013.01); G01N 27/4145 (2013.01); G01N 27/4146 (2013.01); G01N 27/4148 (2013.01); G11C 19/28 (2013.01); H01L 29/0669 (2013.01); H01L 29/1606 (2013.01); H01L 29/0673 (2013.01);
Abstract

A circuit comprising a substrate with sectors on the substrate is provided, each sector comprising clock and data lines, a controller in electrical communication with the clock and data lines, a counter bias line, an amplifier input line and nano-electronic measurement devices on the substrate. A source of each device is coupled to the counter bias line and a drain of each device is coupled to the amplifier input line to obtain an electrical signal on the drain, the identity of which is determined by electrical interaction between the device and a charge label. Each device drain is gated by a corresponding switch between an on state, in which the drain is connected to the amplifier input line, and an off state, in which the drain is isolated from the amplifier input line. The controller controls switch states responsive to clock signal line pulses and data input line data.


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