The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Jul. 10, 2018
Gwangju Institute of Science and Technology, Gwangju, KR;
Sung Yang, Gwangju, KR;
Sung A Hong, Gwangju, KR;
Gwangju Institute of Science and Technology, Gwangju, KR;
Abstract
A diagnosis kit is disclosed. The diagnosis kit according to an embodiment of the present invention includes a concentration channel into which a sample containing a methylated DNA is introduced, a concentration chamber connected to the concentration channel, wherein the methylated DNA is concentrated by an ion concentration polarization (ICP) phenomenon and moves to the concentration chamber, a sensing chamber connected to the concentration chamber to allow the methylated DNA inside the concentration chamber to move, allow the methylated DNA moved from inside of the concentration chamber to be hybridized, and allow a methylated DNA binding protein to be bound to the hybridized methylated DNA, and a sensor configured to acquire a first electrochemical signal inside the sensing chamber when the methylated DNA is hybridized and acquire a second electrochemical signal inside the sensing chamber when the methylated DNA binding protein is bound.