The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Dec. 09, 2019
Lucie Carrier, Hamburg, DE;
Thomas Eschenhagen, Hamburg, DE;
Thomas Voit, London, GB;
Giulia Mearini, Hamburg, DE;
Oliver Mueller, Heikendorf, DE;
Doreen Stimpel, Hamburg, DE;
Lucie Carrier, Hamburg, DE;
Thomas Eschenhagen, Hamburg, DE;
Thomas Voit, London, GB;
Giulia Mearini, Hamburg, DE;
Oliver Mueller, Heikendorf, DE;
Doreen Stimpel, Hamburg, DE;
Julia Mourot-Filiatre, Brasilia, BR;
Other;
Abstract
The present invention relates to a gene therapy vector which is useful in the treatment or prevention of hypertrophic cardiomyopathy in a subject in need thereof. The gene therapy vector of the invention comprises a nucleic acid sequence encoding a cardiac sarcomeric protein and a cardiomyocyte-specific promoter which is operably linked to said nucleic acid sequence. The invention furthermore relates to a cell which comprises the gene therapy vector. Pharmaceutical compositions which comprise the gene therapy vector and/or a cell comprising said vector are also provided. In another aspect, the invention relates to a method for treating or preventing hypertrophic cardiomyopathy in a subject by introducing the gene therapy vector of the invention into a subject in need of treatment.