The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Apr. 08, 2015
Applicant:

Vivabiocell S.p.a., Udine, IT;

Inventors:

Giacomo Cattaruzzi, Fagagna, IT;

Massimo Moretti, Povoletto, IT;

Antonio Sfiligoj, Duino Aurisina, IT;

Francesco Curcio, Pagnacco, IT;

Assignee:

VivaBioCell S.p.A., Udine, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 (2006.01); C12M 1/34 (2006.01); C12M 1/26 (2006.01); C12M 1/00 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
C12M 41/48 (2013.01); C12M 23/20 (2013.01); C12M 23/28 (2013.01); C12M 27/14 (2013.01); C12M 27/16 (2013.01); C12M 29/26 (2013.01); C12M 33/04 (2013.01); C12M 33/08 (2013.01); C12M 41/12 (2013.01);
Abstract

An automated cell culturing device, which expands, detaches and prepares cells, ready to be implanted in vivo is disclosed. The device is composed by a multi-layered cell culture chamber, a cell preparation chamber, and critical parameters control units which automatically drive the cell culture medium circulation, change and refill. The device according to the invention is characterized in that all the components contacting cells and culture medium constitute a totally disposable 'cartridge' in order to avoid cross-contamination and improve safety. The device is particularly useful for expanding and preparing mesenchymal stem cells for osteoarthritis (OA) therapy, and for other cell based therapies in mammals.


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