The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Oct. 23, 2020
Applicant:

Cleveland State University, Cleveland, OH (US);

Inventor:

Moo-Yeal Lee, Pepper Pike, OH (US);

Assignee:

Cleveland State University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); C12M 1/12 (2006.01); C12M 1/00 (2006.01); G01N 33/50 (2006.01); C12M 1/32 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); C12M 23/06 (2013.01); C12M 23/12 (2013.01); C12M 23/20 (2013.01); C12M 23/22 (2013.01); C12M 23/58 (2013.01); C12M 25/06 (2013.01); C12M 29/10 (2013.01); C12N 5/0671 (2013.01); G01N 33/5014 (2013.01); G01N 33/5088 (2013.01);
Abstract

A perfusion plate that can be combined with pillar plates containing cell layers is disclosed. The perfusion plate can have an inflow reservoir and an outflow reservoir connected by at least one channel, which fluidly connects the perfusion wells to the reservoirs for the flow of a fluid such as growth media. A perfusion plate can be part of an assembly containing a pillar plate, a lid, and a transparent bottom for visualizing cell growth in the perfusion wells. The perfusion-pillar plate assembly can facilitate perfusion-based tissue culture and tissue communication for high throughput, high-content, drug screening.


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