The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Jan. 05, 2018
Development of new monoclonal antibodies recognizing human prostate-specific membrane antigen (psma)
Applicants:
The Johns Hopkins University, Baltimore, MD (US);
Institute of Biotechnology Cas, V.v.i., Vestec, CZ;
Inventors:
Cyril Barinka, Vestec, CZ;
Martin G. Pomper, Baltimore, MD (US);
Zora Novakova, Vestec, CZ;
Catherine A. Foss, Baltimore, MD (US);
Assignees:
The Johns Hopkins University, Baltimore, MD (US);
Institute of Biotechnology CAS, V.V.I., Vestec, CZ;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/30 (2006.01); A61K 47/68 (2017.01); A61K 49/00 (2006.01); A61K 51/10 (2006.01); G01N 33/574 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3069 (2013.01); A61K 47/68 (2017.08); A61K 49/0032 (2013.01); A61K 49/0058 (2013.01); A61K 51/1072 (2013.01); G01N 33/57434 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/51 (2013.01); C07K 2317/92 (2013.01);
Abstract
The presently disclosed subject matter provides compositions and methods comprising isolated antibodies that can recognize human prostate-specific membrane antigen (PSMA). The presently disclosed antibodies can be used to for imaging and therapy of PSMA-expressing cancers, such as prostate cancer, in a subject.