The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Jan. 31, 2022
Bristol-myers Squibb Company, Princeton, NJ (US);
Aaron Yamniuk, Vancouver, CA;
Mary Struthers, Edison, NJ (US);
Stanley R. Krystek, Jr., Ringoes, NJ (US);
Akbar Nayeem, Newtown, PA (US);
Ginger Rakestraw, Somerville, MA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The disclosure provides for antibodies that bind CD40, including a humanized antibody. The antibodies bind CD40 and do not exhibit CD40 agonist activity. The antibodies may comprise a modified IgG1 Fc domain, and exhibit minimal activation of immature dendritic cells. Compositions comprising antibodies, methods of use for treatment of diseases involving CD40 activity, and use in the preparation of a medicament for treatment of a disease involving CD40 activity are provided.