The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Aug. 05, 2022
Applicant:
Anaveon Ag, Basel, CH;
Inventors:
Assignee:
Anaveon AG, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/55 (2006.01); C07K 16/24 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/246 (2013.01); C07K 14/55 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01);
Abstract
The present invention relates to immune-stimulating IL-fusion proteins comprising antibodies joined to human interleukin-(hIL-). The invention more specifically relates to humanized monoclonal antibodies or fragments thereof joined to hIL-or variants thereof and displaying a unique capability of preferentially stimulating cytotoxic T cells and NK cells compared to Treg cells. Furthermore, the invention relates to in vitro and in vivo therapeutic applications of the IL-fusion proteins, in particular as an immunotherapy in the treatment of cancer.