The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Jul. 20, 2018
Applicant:
Shanghaitech University, Pudong New Area, CN;
Inventors:
Jia Liu, Shanghai, CN;
Biao Jiang, Shanghai, CN;
Assignee:
ShanghaiTech University, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/33 (2006.01); C07K 19/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/33 (2013.01); C07K 19/00 (2013.01); A61K 38/00 (2013.01); C07K 2319/55 (2013.01); C07K 2319/81 (2013.01);
Abstract
Provided are chimeric polypeptides that include one or more zinc finger motifs fused to a therapeutic peptide such as botulinum neurotoxins (BoNTs). The zinc finger motif may be located at the C-terminal side of the BoNT and the chimeric polypeptide can optionally include two or more such zinc finger motifs. It said the disclosed chimeric polypeptides can be efficiently delivered to a subject transdermally.