The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Sep. 09, 2022
Applicant:

Astrazeneca Ab, Södertälje, SE;

Inventors:

Hans Roland Lönn, Cheshire, GB;

Stephen Connolly, Cheshire, GB;

Steven Swallow, Cheshire, GB;

Staffan Po Karlsson, Molndal, SE;

Carl-Johan Aurell, Molndal, SE;

John Fritiof Pontén, Cheshire, GB;

Kevin James Doyle, Essex, GB;

Amanda Jane Van De Poël, Essex, GB;

Graham Peter Jones, Essex, GB;

David Wyn Watson, Essex, GB;

Jaqueline Anne Macritchie, Essex, GB;

Nicholas John Palmer, Cheshire, GB;

Assignee:

AstraZeneca AB, Södertälje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 267/10 (2006.01); C07D 409/10 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); A61P 11/00 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 267/10 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01);
Abstract

The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.


Find Patent Forward Citations

Loading…